Kidney cancer

Most people with kidney cancer have no symptoms

Doctors find most kidney cancers when they are checking for something else. Signs and symptoms can include:

Not everyone with these symptoms has kidney cancer. If you have any of these symptoms or are worried
always see your doctor

There are some things that can make you more likely to develop kidney cancer. These are called risk factors and they include:

including von Hippel-Lindau disease hereditary papillary RCC Birt Hogg-Dubé syndrome
hereditary leiomyomatosis RCC tuberous sclerosis Lynch syndrome

Having these risk factors doesn’t mean you will develop kidney cancer. Often there is no clear reason for getting kidney cancer.

If you are worried about your risk factors, ask your doctor for advice

To check your general health and look for signs of a problem in the kidneys.

These tests do not diagnose kidney cancer

They may include: blood chemistry tests to measure certain chemicals. Your doctor might ask you to have further tests. These are some the tests you may have: – a specialised imaging test that uses a small amount of radioactive solution to help cancer cells show up brighter on the scan – (if you have had blood in your urine) the doctor puts a small camera into your bladder to see inside – removal of a tissue sample for examination under a microscope.

It is a common way to diagnose cancer, but it is not often needed for kidney cancer before treatment. This is because imaging scans are good at showing if a kidney tumour is cancer. Most kidney cancers are renal cell carcinoma (RCC), sometimes called renal cell adenocarcinoma.

Usually only one kidney is affected, but in rare cases both kidneys can be affected. As the cancer grows, it can spread to areas near the kidney. It may also spread to other parts of the body, such as the lungs or bones.

RCC is the most common type of kidney cancer, but there are other less common types:

Wilms tumour sometimes called nephroblastoma is the most common type of kidney cancer in younger children
but it is still rare. Very rarely
cancer can spread from a primary cancer somewhere else in the body to the kidney (known as secondary cancer)

Stages and grades of cancer describe how far it has spread and how quickly it is growing.

The stage of a cancer means how large it is, where it is, and whether it has spread beyond the kidney. Your doctor will use the results of your tests to assign a stage. Stages 1 and 2 are considered early kidney cancer (only the kidneys are affected).

Stages 3 and 4 are considered advanced kidney cancer (the cancer has spread beyond the kidneys). Ask your doctor or nurse to explain the stage of the cancer. You can also read more from Cancer Council about The grade of the cancer means how quickly a cancer might grow.

Knowing the grade helps your doctor work out the best treatment plan for you. In United States, both the Fuhrman system and the newer International Society of Urological Pathology (ISUP) system may be used to grade kidney cancer. Both systems grade kidney cancer from 1 to 4, with grade 1 being the slowest growing and grade 4 the fastest growing.

When someone is diagnosed with kidney cancer, their doctor will give them a ‘prognosis’. A prognosis is the doctor’s opinion of how likely the cancer will spread and the chances of getting better. A prognosis depends on the type and stage of cancer, as well as the person’s age and general health.

In most cases, the earlier that kidney cancer is diagnosed, the better the chance of successful treatment. If you have kidney cancer, your doctor will talk to you about your individual situation when working out your prognosis.

Every person’s experience is different, and there is support available to you

Treatment for kidney cancer depends on how quickly the cancer is growing. Treatment is different for early kidney cancer and advanced kidney cancer.

You might feel confused or unsure about your treatment options and decisions

It’s okay to ask your treatment team to explain the information to you more than once. It’s often okay to take some time to think about your decisions.

If you are a current smoker, your health care team will advise you to stop smoking before you start treatment.

To work out a plan for quitting, talk to your doctor or call on Tel.

Treatment for early kidney cancer may include: other treatments

When small tumours are found in the kidney, they are less likely to be aggressive and might not grow during a person’s lifetime.

In this case, your doctor might recommend active surveillance, also known as observation. This involves regular ultrasounds or CT scans.

If these imaging tests suggest that the tumour has grown at any time, you will be offered treatment.

Surgery is the main treatment for kidney cancer that has not spread outside the kidney. Depending on the type of kidney cancer, the grade and stage of the cancer, and your general health, you might have one of the following operations: – this is the most common option for small tumours within the kidney.

Only the cancer and a small part of the kidney are removed.

– this is the most common operation for large tumours. The whole affected kidney, a small part of the ureter and the surrounding fatty tissue are removed. The adrenal gland and nearby lymph nodes might also be removed.

Surgery is the most common treatment for early kidney cancer

If you are not well enough for surgery and the tumour is small, your doctor may recommend another type of treatment: – uses heat from a needle to kill the cancer cells. – uses probes to kill the cancer cells by freezing them.

– uses highly targeted radiation to destroy or damage the cancer cells. Treatment for advanced kidney cancer may include: radiation therapy.

Drugs that reach cancer cells throughout the body are called systemic treatments

Targeted therapy and immunotherapy are the main systemic treatments used to control advanced kidney cancer. Since the development of these more effective systemic treatments, chemotherapy is rarely used for kidney cancer. Sometimes when kidney cancer has spread it grows so slowly that it won’t cause any problems for a very long time.

Because of this your doctor may suggest active surveillance, also known as observation, involving regular ultrasounds or CT scans.

If the cancer starts to grow quickly or causes symptoms, your doctor will recommend active treatment. Surgery to remove kidney cancer when the cancer has spread to other parts of the body is called cytoreductive surgery.

This can involve removing the primary cancer in the kidney (nephrectomy), or removing some or all of the tumours that have grown in other parts of the body (metastasectomy). Generally, surgery is not recommended if you are unwell or if the cancer has spread to many places in the body. This is a type of treatment that attacks specific parts of cancer cells with medicines to stop the cancer growing and spreading.

Types of targeted therapy drugs include: There have been many advances in treating advanced kidney cancer with immunotherapy drugs known as checkpoint inhibitors. These use the body’s own immune system to fight cancer. Ask your doctor for more information about immunotherapy for kidney cancer.

Radiation therapy uses a controlled dose of radiation, such as focused x-ray beams, to kill or damage cancer cells.

It is also known as radiotherapy

Radiation therapy might be used in advanced kidney cancer to shrink a tumour and relieve symptoms.

All cancer treatments can have side effects

Your treatment team will discuss these with you before you start treatment. Talk to your doctor or nurse about any side effects you are experiencing. Some side effects can be upsetting and difficult, but there is help if you need it.

Having kidney cancer and treatment can change the way you feel about yourself, other people and sex. These changes can be very upsetting and hard to talk about.

Doctors and nurses are very understanding and can give you some support. You can ask for a referral to a doctor or therapist who specialises in body image, sex and relationships. Advanced cancer usually means cancer that is unlikely to be cured.

Some people can live for many months or years with advanced cancer.

During this time palliative care services can help

Most people continue to have treatment for advanced cancer as part of palliative care, as it helps manage the cancer and improve their day-to-day lives. Many people think that palliative care is for people who are dying but palliative care is for any stage of advanced cancer. There are doctors, nurses and other people who specialise in palliative care.

Treatment can include chemotherapy, radiation therapy or another type of treatment. It can help in these ways: help you to live more comfortably by managing symptoms, like pain. Treatment depends on several things: your preferences and what you want to do.

Ask your doctor about treatment and palliative care services that may help you. Caring for someone with cancer can be difficult sometimes.

If you are caring for someone with kidney cancer, these organisations can help: Tel.

Tel. The kidneys The kidneys are part of the body’s urinary system Kidney cancer is cancer Signs and symptoms of kidney cancer blood in your urine – this may be obvious, or the urine may look dark, rusty or brown pain in your lower back or side a lump in your abdomen constant tiredness unexplained weight loss fever (not caused by a cold or flu Risk factors for kidney cancer smoking obesity – excess body fat may cause changes in certain hormones that can lead to kidney cancer high blood pressure kidney failure – people with end-stage kidney disease family history – people who have family members with kidney cancer, especially a parent, sister or brother inherited conditions Tests for kidney cancer You will probably have urine and blood tests a complete count of the 3 types of blood cells – red blood cells, white blood cells and platelets tests to check how your kidneys are working ultrasound – a scan on the outside of your abdomen to check for cancer CT scan – a scan that takes pictures of the inside of the body MRI scan – a scan that uses magnetism and radio waves to take pictures of the inside of the body bone scan – a scan that uses dye to show changes in your bones PET scan cystoscopy biopsy Types of kidney cancer urothelial carcinoma, sometimes called transitional cell carcinoma, behaves and is treated like bladder cancer , not like RCC Stages and grades of kidney cancer Stages kidney cancer staging Grades Prognosis and survival rates for kidney cancer Treatment for kidney cancer Quitline 13 78 48 Treatment for early kidney cancer active surveillance surgery Active surveillance Surgery Removing part of the kidney, sometimes called a partial nephrectomy Removing the whole kidney, sometimes called a radical nephrectomy Other treatments Thermal ablation Cryotherapy Stereotactic body radiation therapy Treatment for advanced kidney cancer active surveillance surgery targeted therapy immunotherapy Active surveillance Surgery Targeted therapy Immunotherapy Radiation therapy Side effects of treatment for kidney cancer Call Cancer Council ( 13 11 20 or 13 14 50 for an interpreter) or contact cancer support Sexuality and kidney cancer Living with advanced cancer slow down how fast the cancer is growing shrink the cancer where the cancer started how far it has spread your general health Support for carers, family and friends Cancer Council Michigan, 13 11 20 Carer Gateway 1800 422 737 Carers United States 1800 514 845 Where to get help Your GP (doctor) Your treatment team Cancer Council Michigan Cancer information and support line 13 11 20 (or 13 14 50 for an interpreter ) Kidney cancer Cancer Council Michigan, My Cancer Guide Find support services that are right for you.

WeCan website Kidney Health United States 1800 454 363 NURSE-ON-CALL (616) 555-0024.

Key Points

twice as common in men as in women and is the 6th most diagnosed cancer in American men
risk of kidney cancer increases with age, and most cases occur in people over 50 years old
Most people with kidney cancer have no symptoms
Signs and symptoms can include: Not everyone with these symptoms has kidney cancer
If you have any of these symptoms or are worried, always see your doctor