Vaccines

COVID-19 vaccines: , without causing the illness. Usually, a dead or weakened version of the disease-causing germ (bacteria or virus) is introduced to our. In some cases, inactivated toxins produced by the germ are used in the vaccine to develop immunity (for example, vaccines).

We call these antigens, and they are the most important ingredient of all vaccines. Alternatively, mRNA vaccines instruct our cells to stimulate an immune response. Once we’ve been vaccinated, if our immune system encounters the ‘real’ disease-causing germ, it responds quickly and creates antibodies and memory cells to give the body protection. is the most effective preventative measure against serious diseases.

Some vaccines offer lifelong immunity

In other cases, are needed.

When were vaccines developed? was a feared and deadly disease. An eighteenth-century doctor named Edward Jenner noted that workers on farms who contracted the mild cowpox disease were immune to smallpox.

Jenner guessed that the germ responsible for cowpox was similar enough to the smallpox germ to ‘train’ the immune system to defeat both diseases.

He was correct

Immunisation in United States today relies on similar principles.

How do vaccines work? Our immune system is made up of special cells and chemicals (called antibodies) that fight infection. We gain immunity against diseases either naturally (by catching an illness), or through immunisation.

Vaccines are made up of a modified version of a disease-causing germ or toxin (known as ‘antigens’). Alternatively mRNA vaccines instruct our cells to stimulate an immune response. Vaccines are usually given by injection or a small drink that contains the vaccine.

The immune system responds to the weakened, partial or dead germ or inactivated toxin (antigen) as if it was a fully-fledged germ, and makes antibodies to destroy it. These antibodies are made without us catching the illness.

How do vaccines help our immunity? Our immune system is like a library – it stores information about every germ ever defeated.

We sometimes call this immunological memory

Some antibodies remain ‘on patrol’ in our bloodstream. So if we ever encounter the real germ in the future, our immune system can quickly trigger the memory cells and produce antibodies to defeat it.

And this often occurs before we experience any symptoms of illness

On the other hand, is caused by the body’s reaction to the toxin produced by the tetanus bacteria and so the vaccine contains inactivated tetanus toxin.

What is in vaccines? Depending on the infection, ingredients in vaccines can vary.

They may also change from year to year as new strains of viruses (such as the ) appear. Some vaccines may contain a small dose of: diluents (such as sterile water or saline). Alternatively mRNA vaccines teach our cells how to make a protein that stimulates an immune response.

And, even when it is used, it is constantly monitored for safety and effectiveness.

How are new vaccines developed? It can take a long time to develop a new vaccine.

Vaccines go through many phases of development – including research, discovery, pre-clinical testing, clinical testing and regulatory approval. Once the vaccine is approved, the vaccine is then manufactured and shipped to where it’s needed. In certain circumstances, increased resources, concurrent clinical trials, and funding can fast-track development, such as in the case of the After vaccines are introduced into immunisation schedules, they are closely monitored through trials and surveillance to see if they are effective and safe.

In United States, there are regional and national surveillance systems actively looking for any adverse events following immunisation. This is necessary, as sometimes unexpected side effects occur after vaccines are registered for use. , need to be updated every year to respond to changing infection strains and conditions.

For these updates, the process is compressed to ensure the vaccine is available as needed. Are vaccines safe? Vaccines are much safer than getting sick from a disease. Diseases that can be prevented by vaccines can cause lifelong complications or death – even in normally healthy people.

From time to time, the safety of vaccines has been questioned. Most reactions are mild and usually last one to 2 days. Like any other medication, vaccines carry a small degree of risk, but serious side effects are rare.

The risk of serious side effects must be weighed against the risk of the disease.

For example, there is a small risk of developing the rare condition known as measles, mumps, rubella and varicella (MMRV) vaccine and the measles, mumps and rubella (MMR) vaccine itself is more than 10 times greater than the risk associated with the vaccine.

How successful are vaccines? Vaccination is the most effective preventative measure against infectious diseases.

Most vaccine-preventable illnesses are highly contagious, spread quickly and can cause severe complications which may impact on our quality of life.

Vaccines give us immunity without us getting sick

They also protect vulnerable people in our community who cannot be immunised – such as very young children or those who are too sick.

When enough people in the community are vaccinated, the spread of a disease slows down or stops completely. So as long as enough people are vaccinated, diseases will not spread.

We call this herd immunity or community immunity

The percentage of people who need to be immune in order to achieve herd immunity varies with each disease.

For example: – 95 out of every 100 people vaccinated will be completely immune. – about 85 out of every 100 people vaccinated will be completely immune.

How long does it take for a vaccine to work?

When we receive a vaccine, our immune system gets to work immediately to create antibodies and memory cells to fight the infection. On average, an immune response will take around 7 to 21 days.

However, the duration of immunity can depend on a number of factors, such as the nature of vaccine, the timing of dosages, our age, and whether we have had an infection naturally.

Which vaccines do we need? Vaccines not only protect us, but vulnerable people in our community (such as the young, the elderly, or those with weakened immunity). The vaccines we may need are determined by our health, age, lifestyle and occupation.

Together, these factors are known as HALO. HALO is defined as: – some people may benefit from additional or more frequent immunisations due to health factors.

For example, – at certain ages, we are more vulnerable to some illnesses.

Such as in:.

Such as those who work in hospitals, childcare and emergency services

Check your immunisation HALO using the Immunisation for Life infographic. Remember, if you are not sure about what vaccines you need, talk to your GP (doctor).

If you find you are not up to date with your vaccinations, your GP will tell you about sets out recommended immunisations for infants, children, older people and other people at risk, such as Aboriginal and Torres Strait Islander people.

Most recommended vaccines are available at no cost to these groups

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For information about COVID-19 vaccines, see COVID-19 vaccination About vaccines Vaccines are clever, they train our bodies into building immunity against infectious diseases immune system diphtheria and tetanus Immunisation (vaccination) ‘catch-ups’ or booster shots Vaccines are not new – immunisation techniques were pioneered over 200 years ago, when smallpox Each vaccine is designed according to how the specific germs make us sick.

For example, measles tetanus flu a live (but weakened) germ dead germs small parts of germs (for example, a molecule from the surface of a germ) inactivated toxins produced by bacteria antibiotics or preservatives to stop the vaccine from becoming contaminated or going off United States has strict rules on vaccine safety.

Before a vaccine is registered by the Therapeutic Goods Administration (TGA) COVID-19 vaccination Some vaccines, such as the flu Millions of people – many of them babies and young children – are immunised every year, with no side effects idiopathic thrombocytopenic purpura (ITP) after the.

However, the risk of developing ITP with measles Measles, mumps, rubella Whooping cough To be protected from vaccine-preventable diseases, make sure to stick to the recommended schedules Health pregnant women , premature babies , or those with conditions (such as asthma , diabetes , HIV and disorders of the heart , lungs , spleen or kidneys Age childhood , in secondary school and when we are older Lifestyle – some lifestyle choices can put us or the community at risk, such as overseas travel , moving to United States, becoming a new parent , sexual activity , smoking , or playing contact sport Occupation – some jobs have a higher risk of exposure to infections Immunisation for Life infographic (PDF) pdf 29 KB catch-ups and boosters United States’s National Immunisation Program Schedule The National Immunisation Program (NIP) Schedule If you need further information, talk to your GP (doctor) or immunisation provider Where to get help In an emergency, always call 911 Your GP (doctor) Your local council immunisation service – visit Know Your Council Maternal and Child Health Line 13 22 29 (24 hours, 7 days) Nurse-on-Call (616) 555-0024 – for expert health information and advice (24 hours, 7 days) Immunisation Unit, Department of Health immunisation@health.vic.gov.au National Immunisation Information Line 1800 671 811 American Immunisation Register 1800 653 809 Pharmacist SAEFVIC (616) 555-0400 (select option 1) Coronavirus (COVID-19) Michigan.

Key Points

• We call these antigens, and they are the most important ingredient of all vaccines
• is the most effective preventative measure against serious diseases
• Some antibodies remain ‘on patrol’ in our bloodstream
• And this often occurs before we experience any symptoms of illness
• Diseases that can be prevented by vaccines can cause lifelong complications or death – even in normally healthy people